Synthesis of Adenylyl-(3'-5')-3'-O-methylguanosine and of Guanylyl-(3'-5')-3'-O-methylguanosine.
نویسندگان
چکیده
منابع مشابه
Novel synthesis of 2'-O-methylguanosine.
An efficient and chemoselective synthesis of 2'-O-methylguanosine (6) has been accomplished in high yield without protection of the guanine base. The salient feature of the synthesis of 6 lies in the application of methylene-bis-(diisopropylsilyl chloride), (MDPSCl(2), 2) as a new 3',5'-O-protecting group for nucleosides. Use of CH(3)Cl as a weak electrophile and NaHMDS as a mild base was cruci...
متن کاملSYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2’-n-BUTYLBENZOFURAN-3’-YL)-5-ARYL-4, 5-DIHYDRO-1H-PYRAZOLES.
3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve, Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activi...
متن کاملSYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2’-n-BUTYLBENZOFURAN-3’-YL)-5-ARYL-4, 5-DIHYDRO-1H-PYRAZOLES.
3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve, Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activi...
متن کاملSYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 6-CARBETHOXY-5-(3'-BROMOPHENYL)-3-ARYL-2-CYCLOHEXENONES AND 6-ARYL-4-(3'-BROMOPHENYL)-3-OXO-2,3A,4,5-TETRAHYDRO-2H-INDAZOLES
6-Carbethoxy-5-(3'-bromophenyl)-3-aryl-2-cyclohexenones 2a-j were obtained from the1-Aryl-3-(3'-bromophenyl)-2-propene-1-ones 1a-j by Micheal addition of ethyl acetoacetate, followed by internal Claisen condensation. Reaction of 2a-j with hydrazine hydrate afforded the corresponding 6-Aryl-4-(3'-bromophenyl)-3-oxo-2,3a,4,5-tetrahydro-2H-indazoles 3a-j. The structures of newly synthesized compou...
متن کاملPoly[[diaquabis(2,2′-bipyridine-κ2 N,N′)(μ3-5-hydroxyisophthalato-κ5 O 1,O 1′:O 3,O 3′:O 3′)(μ3-5-hydroxyisophthalato-κ4 O 1,O 1′:O 3:O 3′)(μ2-5-hydroxyisophthalato-κ3 O 1,O 1′:O 3)didysprosium(III)] dihydrate]
The polymeric title compound, {[Dy(2)(C(8)H(4)O(5))(3)(C(10)H(8)N(2))(2)(H(2)O)(2)]·2H(2)O}(n), contains two independent Dy(III) ions, both of which are nine-coordinated in a distorted tricapped trigonal-prismatic geometry. One Dy(III) ion is coordinated by five 5-hy-droxy-isophthalate (hip) ligands and one 2,2'-bipyridine (bpy) ligand and the other by three hip ligands, one bpy ligand and two ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1980
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.34b-0753